سعر ستابلنتين 800مجم 10 قرص 2022

Film-coated tablets containing gabapentin 800 mg (anti-epileptic, GABA analogue), made by Mepaco; pack of 10 tablets.

• Management of postherpetic neuralgia in adults.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy of partial-onset seizures, with or without secondary generalisation, in adults and children 3 years and older with epilepsy.Population: Adults and children >=3 yearsDailyMed (U.S. National Library of Medicine)

• Epilepsy trials (over 12 years): somnolence (19%), dizziness (17%) and ataxia (13%) more often than placebo; postherpetic neuralgia trials: dizziness (28%) and somnolence (21%); peripheral oedema and ataxia increased with age.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to gabapentin or any ingredient of the product.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• DRESS/multiorgan hypersensitivity (sometimes fatal) and anaphylaxis/angioedema have occurred; stop the drug if no alternative cause is found.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Somnolence, sedation and dizziness; patients should not drive or operate complex machinery until they know how they are affected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs increase the risk of suicidal thoughts or behaviour; monitor for depression and mood changes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Opioids (morphine, hydrocodone, oxycodone, buprenorphine)Respiratory depression and sedation, sometimes fatal; morphine may increase gabapentin levels, gabapentin decreases hydrocodone exposure.DailyMed (U.S. National Library of Medicine)
• Antacids containing aluminium and magnesium hydroxideReduce gabapentin bioavailability by about 20% (about 10% if gabapentin is taken 2 hours after the antacid).DailyMed (U.S. National Library of Medicine)

• Published cohort data have not shown an increased risk of major birth defects or miscarriage, with methodological limitations; animal studies showed developmental toxicity. Extended use with opioids near delivery may increase neonatal withdrawal risk. A North American AED pregnancy registry exists.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Gabapentin is secreted in human milk; effects on the breastfed infant and on milk production are unknown. Weigh benefits of breastfeeding against maternal need.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Gabapentin: Structurally related to GABA but does not act on GABA receptors; binds with high affinity to the alpha-2-delta subunit of voltage-gated calcium channels (US label).