سعر جيديماديل 3 مجم 30 قرص 2024

Glimepiride 3 mg oral tablets (3 strips of 10) by Jedco International, a sulfonylurea used for type 2 diabetes.

• Treatment of type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate.Population: Adults with type 2 diabeteselectronic medicines compendium (emc), UK

• Rare: hypoglycaemia, thrombocytopenia, leukopenia, agranulocytosis, haemolytic anaemia, dysgeusia; very rare: nausea, vomiting, diarrhoea, abdominal pain, hepatitis, leukocytoclastic vasculitis, hypersensitivity reactions; transient visual disturbances may occur at the start of treatment.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to glimepiride, other sulfonylureas or sulfonamides, or to any excipient; type 1 diabetes; diabetic coma; ketoacidosis; severe renal or hepatic function disorders.International label, same formulation · electronic medicines compendium (emc), UK

• Hypoglycaemia may occur with irregular or skipped meals, undernutrition, alcohol, unaccustomed exercise, renal or hepatic dysfunction or interacting drugs; severe or prolonged hypoglycaemia requires immediate medical treatment.International label, same formulation · electronic medicines compendium (emc), UK
• Patients with G6PD deficiency may develop haemolytic anaemia with sulfonylureas; consider a non-sulfonylurea alternative.International label, same formulation · electronic medicines compendium (emc), UK
• Contains lactose; not for patients with hereditary galactose intolerance, total lactase deficiency or glucose-galactose malabsorption.International label, same formulation · electronic medicines compendium (emc), UK

• CYP2C9 inhibitors (e.g. fluconazole) and inducers (e.g. rifampicin)Glimepiride is metabolised by CYP2C9; fluconazole roughly doubles glimepiride AUC, rifampicin may reduce its effect.electronic medicines compendium (emc), UK
• Insulin, other oral antidiabetics, salicylates, fibrates, ACE inhibitors, coumarins, fluoxetine, MAO inhibitors, quinolones, clarithromycin, miconazole and othersMay potentiate the blood-glucose-lowering effect and cause hypoglycaemia.electronic medicines compendium (emc), UK
• Beta-blockers, clonidine, guanethidine, reserpineMay potentiate or weaken the hypoglycaemic effect and mask signs of hypoglycaemia (adrenergic counter-regulation).electronic medicines compendium (emc), UK

• No adequate data in pregnant women; animal reproductive toxicity likely related to hypoglycaemia. Glimepiride should not be used during the whole pregnancy; switch to insulin as soon as pregnancy is planned or discovered.International label, same formulation · electronic medicines compendium (emc), UK
• Excretion in human milk is unknown (excreted in rat milk); because of the risk of hypoglycaemia in nursing infants, breast-feeding is advised against during treatment.International label, same formulation · electronic medicines compendium (emc), UK

• Glimepiride: Sulfonylurea that lowers blood glucose mainly by stimulating insulin release from functioning pancreatic beta cells (US label).