سعر جينوتروبين 4 وحدة دولية فيال 2022

Somatropin (recombinant human growth hormone) 4 IU vial for injection.

• Growth failure due to inadequate secretion of endogenous growth hormone.Population: PediatricDailyMed (U.S. National Library of Medicine)
• Growth failure due to Prader-Willi syndrome.Population: PediatricDailyMed (U.S. National Library of Medicine)
• Growth failure in children born small for gestational age who fail to show catch-up growth by age 2 years.Population: PediatricDailyMed (U.S. National Library of Medicine)

• Common reactions include injection-site reactions, lipoatrophy and headache; in adults oedema, arthralgia, myalgia, paraesthesia and carpal tunnel syndrome.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Acute critical illness after open heart or abdominal surgery, multiple accidental trauma or acute respiratory failure.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Prader-Willi syndrome in patients who are severely obese, have a history of upper airway obstruction or sleep apnoea, or have severe respiratory impairment (fatalities reported).General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Active malignancy.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Increased risk of a second neoplasm in childhood cancer survivors treated with radiation; monitor for progression or recurrence of tumours.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• May decrease insulin sensitivity; monitor glucose, especially in patients with diabetes or risk factors.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Intracranial hypertension with papilloedema may occur, usually within the first 8 weeks; perform fundoscopy before and during treatment.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Glucocorticoids (replacement therapy)Somatropin inhibits 11beta-HSD1 and may unmask central hypoadrenalism or require higher glucocorticoid doses; excessive glucocorticoid may blunt the growth response.DailyMed (U.S. National Library of Medicine)
• CYP450-metabolised drugs (e.g. sex steroids, corticosteroids, anticonvulsants, cyclosporine)Somatropin may alter the clearance of these drugs; careful monitoring is advised.DailyMed (U.S. National Library of Medicine)
• Oral oestrogenWomen on oral oestrogen may need larger somatropin doses.DailyMed (U.S. National Library of Medicine)

• Available human data are insufficient to establish a drug-associated risk of major birth defects or miscarriage; no adverse embryo-fetal effects were seen in rats and rabbits given somatropin.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• No data on somatropin in human milk or effects on the breastfed infant; exogenous somatropin does not increase growth hormone in breast milk according to the label.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

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