سعر جنتاميسين 40مجم/مل 6 امبولات 2023

Gentamicin 40 mg/ml injection, pack of 6 ampoules, by Memphis (Egypt), an aminoglycoside antibiotic for serious bacterial infections.

• Treatment of serious infections caused by susceptible strains of Pseudomonas aeruginosa, Proteus species, E. coli, Klebsiella-Enterobacter-Serratia, Citrobacter and Staphylococcus species, including bacterial neonatal sepsis, septicaemia and serious CNS, urinary tract, respiratory, gastrointestinal, skin, bone and soft-tissue infections.Population: Adults, children, infants and neonates with serious susceptible infectionsDailyMed (U.S. National Library of Medicine)

• Nephrotoxicity and neurotoxicity (ototoxicity: dizziness, vertigo, tinnitus, roaring in the ears and hearing loss) are the main adverse reactions.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to gentamicin; a history of hypersensitivity or serious toxic reactions to other aminoglycosides may contraindicate use because of cross-sensitivity.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: potential nephrotoxicity, ototoxicity (often irreversible vestibular and auditory) and neurotoxicity; monitor renal and eighth cranial nerve function and serum concentrations, especially in elderly or dehydrated patients and with high doses or prolonged therapy.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Avoid concurrent or sequential use of other neurotoxic and/or nephrotoxic drugs and potent diuretics such as ethacrynic acid and furosemide.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Neuromuscular blockade and respiratory paralysis may occur, especially with anaesthesia or neuromuscular blocking agents.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Potent diuretics (ethacrynic acid, furosemide)Avoid: may cause ototoxicity and, given IV, may enhance aminoglycoside toxicity by altering serum and tissue concentrations.DailyMed (U.S. National Library of Medicine)
• CephalosporinsIncreased nephrotoxicity has been reported with concomitant use.DailyMed (U.S. National Library of Medicine)
• Other neurotoxic/nephrotoxic drugs (e.g. cisplatin, polymyxin B, colistin, amphotericin B, vancomycin, other aminoglycosides)Avoid concurrent or sequential use because of additive toxicity.DailyMed (U.S. National Library of Medicine)

• Aminoglycosides can cause fetal harm when given to a pregnant woman (total irreversible bilateral congenital deafness has been reported with streptomycin); inform the patient of the potential hazard if used during pregnancy.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Gentamicin: Bactericidal; its most important effect is inhibition of bacterial protein synthesis at the level of the 30S ribosomal subunit; also affects plasma-membrane integrity and RNA metabolism (UK SmPC, gentamicin eye/ear drops).