سعر جلوكوريل 4 مجم 10 أقراص 2022

Egyptian Glucoryl 4 mg glimepiride film-coated tablets (10 tablets) by Hikma Pharma; oral sulfonylurea for type 2 diabetes.

• Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes (not for type 1 diabetes or diabetic ketoacidosis)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypoglycaemia is the main adverse reaction; postmarketing reports include serious hypersensitivity, haemolytic anaemia and impaired liver function (cholestasis, jaundice, hepatitis).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to glimepiride or any ingredient; history of allergic reaction to sulfonamide derivatives.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Can cause hypoglycaemia, sometimes severe (caution with driving/machinery); higher risk in elderly, renal impairment, poor food intake or with other glucose-lowering drugs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Serious hypersensitivity reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome); haemolytic anaemia, especially with G6PD deficiency; label warning on increased risk of cardiovascular mortality with sulfonylureas (UGDP study).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Oral miconazoleSevere hypoglycaemia has been reported with concomitant use.DailyMed (U.S. National Library of Medicine)
• CYP2C9 inhibitors and inducersMay alter glimepiride plasma concentrations and glycaemic control.DailyMed (U.S. National Library of Medicine)
• ColesevelamReduces glimepiride absorption; give glimepiride at least 4 hours before colesevelam.DailyMed (U.S. National Library of Medicine)

• US label: available data have not identified a drug-associated risk of major birth defects or miscarriage; sulfonylureas may cause neonatal hypoglycaemia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• US label: monitor breastfed infants for signs of hypoglycaemia (jitteriness, cyanosis, apnoea, hypothermia, excessive sleepiness, poor feeding).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Glimepiride: Lowers blood glucose mainly by stimulating insulin release from functioning pancreatic beta cells.