سعر جاوتيلس 30 قرص 2025

Probenecid 500 mg + colchicine 0.5 mg tablets (October Pharma), 3 strips x 10 tablets per pack.

• Treatment of chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout.Population: Adults
• Treatment of chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout.Population: AdultsDailyMed (U.S. National Library of Medicine)

• US: probenecid: headache, dizziness, anorexia, nausea, vomiting, urinary frequency, hypersensitivity, nephrotic syndrome, uric acid stones, aplastic anaemia, haemolytic anaemia (possibly G6PD-related); colchicine: peripheral neuritis, muscular weakness, nausea, vomiting, abdominal pain, diarrhoea.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• US: hypersensitivity; children under 2 years; known blood dyscrasias or uric acid kidney stones; do not start therapy until an acute gout attack has subsided; colchicine component contraindicated in pregnancy.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• US: exacerbation of gout may occur; salicylates antagonize the uricosuric action of probenecid (use acetaminophen for mild analgesia); severe allergic reactions and anaphylaxis have been reported rarely.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• US: hematuria, renal colic, costovertebral pain and uric acid stones may occur; liberal fluid intake and urine alkalinisation are recommended; use with caution in history of peptic ulcer.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• MethotrexateUS: probenecid reduces renal excretion of methotrexate and raises its levels; reduce methotrexate dose and monitor.DailyMed (U.S. National Library of Medicine)
• Penicillins and other beta-lactam antibioticsUS: probenecid increases and prolongs plasma levels of penicillin and other beta-lactams.DailyMed (U.S. National Library of Medicine)
• SalicylatesUS: salicylates antagonize the uricosuric action of probenecid; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• US: the colchicine component is contraindicated in pregnancy.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

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