سعر هيبيوروكسيم 125 مجم 10 قرص 2022

Cefuroxime 125 mg film-coated tablets; 10 film-coated tablets.

• Mild-to-moderate pharyngitis/tonsillitis caused by susceptible Streptococcus pyogenes.Population: Adults and pediatric patients 13 years and olderDailyMed (U.S. National Library of Medicine)
• Acute bacterial otitis media.Population: Pediatric patients who can swallow tablets wholeDailyMed (U.S. National Library of Medicine)
• Acute bacterial maxillary sinusitis.Population: Adults and pediatric patientsDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (≥3%): diarrhea, nausea/vomiting, Jarisch-Herxheimer reaction and vaginitis (early Lyme disease).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity (e.g., anaphylaxis) to cefuroxime axetil or to other beta-lactam antibacterial drugs (penicillins, cephalosporins).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Serious and occasionally fatal anaphylactic reactions have been reported with beta-lactams; ask about prior penicillin/cephalosporin allergy and discontinue if a reaction occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhea (CDAD) may occur, ranging from mild diarrhea to fatal colitis; evaluate patients who develop diarrhea.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Drugs that reduce gastric acidity (antacids, H2-receptor antagonists, proton pump inhibitors)May lower cefuroxime axetil bioavailability; give at least 1 hour before or 2 hours after short-acting antacids; avoid H2 antagonists and PPIs.DailyMed (U.S. National Library of Medicine)
• ProbenecidIncreases systemic exposure to cefuroxime; coadministration is not recommended.DailyMed (U.S. National Library of Medicine)

• Published epidemiologic data over several decades with cephalosporins, including cefuroxime axetil, have not established drug-associated risks of major birth defects, miscarriage or adverse maternal/fetal outcomes; animal studies showed no adverse developmental outcomes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Cefuroxime is present in human milk; estimated infant dose is less than 1% of the adult dose. Weigh breastfeeding benefits against the mother's clinical need and potential infant effects.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cefuroxime: Bactericidal beta-lactam that binds penicillin-binding proteins and inhibits bacterial cell-wall synthesis.