سعر هيدراسيك 100مجم 10 كبسولات 2024

Racecadotril 100 mg hard capsules (Abbott), an intestinal enkephalinase inhibitor (antisecretory antidiarrhoeal), pack of 10 capsules.

• Symptomatic treatment of acute diarrhoea in adults when causal treatment is not possible; may be used as complementary treatment when causal treatment is possible.Population: AdultsHealth Products Regulatory Authority (HPRA), Ireland

• Common: headache. Uncommon: rash, erythema. Not known: erythema multiforme, tongue/face/lip/eyelid oedema, angioedema, urticaria, erythema nodosum, papular rash, prurigo, pruritus, toxic skin eruption, DRESS, anaphylactic shock.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Hypersensitivity to racecadotril or to any of the excipients.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Racecadotril does not replace usual rehydration; bloody or purulent stools with fever may indicate invasive bacterial infection or other severe disease. Not tested in antibiotic-associated diarrhoea (should not be used there); chronic diarrhoea insufficiently studied; availability may be reduced with prolonged vomiting.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Skin reactions, angioedema and severe cutaneous adverse reactions including DRESS have been reported; stop immediately if they occur and do not reintroduce. Careful risk/benefit assessment before use in patients on ACE inhibitors (bradykinin-mediated angioedema).International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Contains lactose: not for patients with galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• ACE inhibitors and other drugs causing bradykinin-mediated angioedema (angiotensin II antagonists, mTOR inhibitors, gliptins, estramustine, sacubitril, alteplase)Concomitant use may increase the risk of angioedema and is not recommended.Health Products Regulatory Authority (HPRA), Ireland

• No adequate data in pregnant women; animal studies show no harmful effects, but as no specific clinical studies exist racecadotril should not be administered to pregnant women.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Excretion in human milk unknown; should not be administered to breastfeeding women.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Racecadotril: Prodrug hydrolysed to thiorphan, which inhibits intestinal enkephalinase, prolonging enkephalin action and reducing intestinal hypersecretion of water and electrolytes without changing transit time (Irish SmPC 5.1).