سعر ايموديوم انستانت 2مجم 6 اقراص ذائبة بالفم 2024

Loperamide hydrochloride 2 mg orodispersible tablets (6 tablets), McNeil Products Ltd., marketed in Egypt via Johnson & Johnson Scientific Office; antidiarrhoeal.

• Symptomatic treatment of acute diarrhoea in adults and children aged 12 years and overPopulation: Adults and children >=12 yearselectronic medicines compendium (emc), UK
• Symptomatic treatment of acute episodes of diarrhoea associated with irritable bowel syndrome in adults aged 18 and over, after initial diagnosis by a doctorPopulation: Adults >=18 yearselectronic medicines compendium (emc), UK

• Most common in acute diarrhoea trials: constipation (2.7%), flatulence (1.7%), headache (1.2%) and nausea (1.1%); rare serious reactions include hypersensitivity, ileus and toxic megacolon.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to loperamide or any excipient; children under 12 years.International label, same formulation · electronic medicines compendium (emc), UK
• Acute dysentery (blood in stool and high fever), acute ulcerative colitis, bacterial enterocolitis caused by invasive organisms (Salmonella, Shigella, Campylobacter) and pseudomembranous colitis associated with broad-spectrum antibiotics.International label, same formulation · electronic medicines compendium (emc), UK
• Do not use when inhibition of peristalsis must be avoided (risk of ileus, megacolon, toxic megacolon); stop promptly if constipation, abdominal distension or ileus develop.International label, same formulation · electronic medicines compendium (emc), UK

• Treatment is symptomatic; fluid and electrolyte replacement takes priority, especially in children and frail or elderly patients. Stop and consult a doctor if there is no improvement within 48 hours.International label, same formulation · electronic medicines compendium (emc), UK
• Cardiac events including QT and QRS prolongation and torsade de pointes have been reported with overdose; do not exceed the recommended dose. Overdose may unmask Brugada syndrome. Abuse and misuse have been reported.International label, same formulation · electronic medicines compendium (emc), UK
• Patients with AIDS should stop at the first signs of abdominal distension (toxic megacolon reported). The tablets contain aspartame (phenylalanine source), sulphites and benzyl alcohol among excipients.International label, same formulation · electronic medicines compendium (emc), UK

• P-glycoprotein / CYP3A4 / CYP2C8 inhibitors (quinidine, ritonavir, itraconazole, ketoconazole, gemfibrozil)Raise loperamide plasma levels about 2- to 5-fold (quinidine/ritonavir 2-3x, itraconazole 3-4x, ketoconazole 5x, gemfibrozil about 2x); clinical relevance at recommended doses is unknown.electronic medicines compendium (emc), UK
• Oral desmopressinCo-administration increased desmopressin plasma concentrations about 3-fold, presumably due to slower GI motility.electronic medicines compendium (emc), UK

• Safety in human pregnancy is not established although animal studies show no teratogenic effects; as with other drugs, use is not advisable in pregnancy, especially in the first trimester.International label, same formulation · electronic medicines compendium (emc), UK
• Small amounts may appear in human milk; not recommended during breastfeeding.International label, same formulation · electronic medicines compendium (emc), UK

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