سعر هيدراسيك رضع 10مجم 10 اكياس 2024

Racecadotril 10 mg granules for oral suspension in sachets (Abbott), an intestinal enkephalinase inhibitor (antisecretory antidiarrhoeal), pack of 16 sachets.

• Complementary symptomatic treatment of acute diarrhoea in infants older than 3 months and children, together with oral rehydration and usual support measures, when these alone are insufficient and causal treatment is not possible.Population: Infants older than 3 months and children <13 kgHealth Products Regulatory Authority (HPRA), Ireland

• Uncommon: rash, erythema. Not known: erythema multiforme, tongue/face/lip/eyelid oedema, angioedema, urticaria, erythema nodosum, papular rash, prurigo, pruritus, toxic skin eruption, DRESS, anaphylactic shock.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Hypersensitivity to racecadotril or to any of the excipients.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Contains sucrose: contraindicated in hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Racecadotril does not replace usual rehydration; bloody or purulent stools with fever may indicate invasive bacterial infection or other severe disease. Not tested in antibiotic-associated diarrhoea (should not be used there); chronic diarrhoea insufficiently studied; availability may be reduced with prolonged vomiting.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Skin reactions, angioedema and severe cutaneous adverse reactions including DRESS have been reported; stop immediately if they occur and do not reintroduce. Careful risk/benefit assessment before use in patients on ACE inhibitors (bradykinin-mediated angioedema).International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Contains sucrose (per sachet: 966.5 mg); take into account in diabetes and in the daily sugar intake.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• ACE inhibitors and other drugs causing bradykinin-mediated angioedema (angiotensin II antagonists, mTOR inhibitors, gliptins, estramustine, sacubitril, alteplase)Concomitant use may increase the risk of angioedema and is not recommended.Health Products Regulatory Authority (HPRA), Ireland

• No adequate data in pregnant women; animal studies show no harmful effects, but as no specific clinical studies exist racecadotril should not be administered to pregnant women.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Excretion in human milk unknown; should not be administered to breastfeeding women.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Racecadotril: Prodrug hydrolysed to thiorphan, which inhibits intestinal enkephalinase, prolonging enkephalin action and reducing intestinal hypersecretion of water and electrolytes without changing transit time (Irish SmPC 5.1).