سعر هايبريوم 1 مجم 20 قرص 2022

Hyperium rilmenidine 1 mg tablets, pack of 20 (2 x 10), by Servier (Egypt listing); centrally acting antihypertensive.

• Arterial hypertension.Population: Adults (including elderly and diabetic hypertensive patients)Base de Données Publique des Médicaments (ANSM, France)

• Common: anxiety, depression, insomnia, somnolence, headache, vertigo, palpitations, cold extremities, gastralgia, dry mouth, diarrhoea, constipation, pruritus, rash, muscle cramps, sexual dysfunction, asthenia, fatigue, oedema. Uncommon: hot flushes, orthostatic hypotension, nausea. Not known: bradycardia.International label, same product · Base de Données Publique des Médicaments (ANSM, France)

• Hypersensitivity to rilmenidine or excipients; severe depressive states; severe renal insufficiency (creatinine clearance <15 ml/min).International label, same product · Base de Données Publique des Médicaments (ANSM, France)

• Never stop abruptly; reduce the dose progressively. Regular medical supervision in patients with recent vascular events (stroke, myocardial infarction).International label, same product · Base de Données Publique des Médicaments (ANSM, France)
• Risk of reduced heart rate and bradycardia: assess carefully and monitor heart rate (especially in the first 4 weeks) in patients with bradycardia or risk factors (elderly, sinus disease, AV block, heart failure).International label, same product · Base de Données Publique des Médicaments (ANSM, France)
• Alcohol, beta-blockers used for heart failure and sodium oxybate are not recommended in combination. Contains lactose (not for galactose intolerance, total lactase deficiency or glucose-galactose malabsorption).International label, same product · Base de Données Publique des Médicaments (ANSM, France)

• AlcoholIncreased sedative effect; avoid alcoholic drinks and alcohol-containing medicines (combination not recommended).Base de Données Publique des Médicaments (ANSM, France)
• Beta-blockers used in heart failureNot recommended: central reduction of sympathetic tone is harmful in heart failure treated with beta-blockers.Base de Données Publique des Médicaments (ANSM, France)
• Sodium oxybateNot recommended: increased central depression.Base de Données Publique des Médicaments (ANSM, France)

• No or limited human data (<300 pregnancies); animal studies show no harmful reproductive effects; as a precaution, preferably avoid during pregnancy.International label, same product · Base de Données Publique des Médicaments (ANSM, France)
• Excretion in human milk unknown (excreted in animal milk); a risk to infants cannot be excluded; must not be used during breastfeeding.International label, same product · Base de Données Publique des Médicaments (ANSM, France)

• Rilmenidine: Oxazoline acting on bulbar vasomotor structures and peripherally, with greater selectivity for imidazoline receptors than for cerebral alpha-2 adrenoceptors (French SmPC).