سعر باي بريتريكس أرجنين 5 مجم/1.25 مجم 15 قرص مغلف (ملغى) 2026

Bi-Preterax Arginine 5 mg/1.25 mg film-coated tablets (perindopril arginine / indapamide), pack of 15; Servier. Egyptian listing marked cancelled.

• Essential hypertension in adults whose blood pressure is not adequately controlled on perindopril alonePopulation: AdultsUK eMC / MHRA SmPC

• Common with perindopril: dizziness, headache, cough, hypotension, GI symptoms, rash, asthenia. With indapamide: hypokalaemia, hypersensitivity/maculopapular rashes. About 4% on the combination experience K+ <3.4 mmol/l.International label, same formulation · UK eMC / MHRA SmPC

• Hypersensitivity to perindopril/ACE inhibitors, indapamide/sulfonamides, or excipients; history of ACEI-related angioedema; hereditary/idiopathic angioedema; 2nd/3rd trimester pregnancy; concomitant aliskiren in diabetes or GFR <60; sacubitril/valsartan; severe renal impairment (CrCl <30); severe hepatic impairment/hepatic encephalopathy; hypokalaemia; dialysis patients; untreated decompensated heart failure.International label, same formulation · UK eMC / MHRA SmPC

• Monitor electrolytes (especially potassium), creatinine and blood pressure. Risk of angioedema, hypotension, renal impairment, dual RAAS blockade hazards, and indapamide-related hypokalaemia/photosensitivity. Contains lactose.International label, same formulation · UK eMC / MHRA SmPC

• LithiumMajorUsually not recommended; reversible lithium toxicity reported with ACE inhibitors.UK eMC / MHRA SmPC
• Potassium-sparing diuretics / potassium salts; NSAIDs; aliskiren; sacubitril/valsartanMajorHyperkalaemia / renal risk with K-sparing agents and NSAIDs; aliskiren and sacubitril/valsartan contraindicated in stated settings.UK eMC / MHRA SmPC

• Not recommended in first trimester; contraindicated in second and third trimesters (ACE inhibitor fetotoxicity: oligohydramnios, neonatal renal failure, hypotension, hyperkalaemia).International label, same formulation · UK eMC / MHRA SmPC
• Not recommended during lactation.International label, same formulation · UK eMC / MHRA SmPC

• Perindopril arginine: Inhibits angiotensin-converting enzyme, reducing conversion of angiotensin I to the vasoconstrictor angiotensin II and the degradation of bradykinin.
• Indapamide: Inhibits sodium reabsorption in the cortical diluting segment, increasing urinary sodium and chloride excretion.