سعر سلفاجرين 1% كريم 80 جم 2026

Silver sulfadiazine 1% topical cream, 80 gm tube, El Nile (Egypt).

• Adjunct for prevention and treatment of wound sepsis in second- and third-degree burnsPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Transient leukopenia (neutropenia, onset 2-4 days); infrequently skin necrosis, erythema multiforme, skin discoloration, burning sensation, rashes, interstitial nephritis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to silver sulfadiazine or any ingredient; pregnant women approaching or at term, premature infants and newborns in the first 2 months (kernicterus risk).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Systemic absorption depends on burn area; sulfonamide reactions possible, including blood dyscrasias, SJS/TEN, hepatitis and toxic nephrosis; cross-sensitivity with other sulfonamides.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Hemolysis possible in G6PD deficiency; fungal proliferation in/below eschar may occur; avoid eye contact; topical use only.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• CimetidineIncreased incidence of leukopenia reported with concurrent use.DailyMed (U.S. National Library of Medicine)
• Topical proteolytic enzymesSilver may inactivate topical proteolytic enzymes.DailyMed (U.S. National Library of Medicine)

• No fetal harm in rabbit studies; no adequate human studies; use in pregnancy only if clearly justified, especially near term (contraindicated at or near term).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether excreted in milk; sulfonamides are excreted and increase kernicterus risk - decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Silver sulfadiazine: Bactericidal for many Gram-negative and Gram-positive bacteria and active against yeast; acts on the cell membrane and cell wall (US Silvadene label).