سعر ايكاندرا 50مجم 30 قرص 2024

Vildagliptin 50 mg tablets, pack of 30 (3 strips), by Mash Premiere (Egypt); oral DPP-4 inhibitor for type 2 diabetes.

• Adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus: as monotherapy when metformin is inappropriate due to contraindications or intolerance, or in combination with other medicinal products for diabetes, including insulin, when these do not provide adequate glycaemic control.Population: Adultselectronic medicines compendium (emc), UK

• Adverse reactions in controlled studies and post-marketing include nasopharyngitis (very common), upper respiratory tract infection, dizziness, headache, tremor, blurred vision and constipation (common), and hypoglycaemia (uncommon); most were mild and transient.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to vildagliptin or to any of the excipients.International label, same formulation · electronic medicines compendium (emc), UK

• Not a substitute for insulin in insulin-requiring patients; should not be used in type 1 diabetes or for diabetic ketoacidosis.International label, same formulation · electronic medicines compendium (emc), UK
• Rare cases of hepatic dysfunction (including hepatitis) have been reported; patients who develop jaundice or other signs of liver dysfunction should discontinue and not restart after LFT normalisation.International label, same formulation · electronic medicines compendium (emc), UK
• Acute pancreatitis has been associated with vildagliptin: discontinue if suspected and do not restart if confirmed; use caution with a history of acute pancreatitis.International label, same formulation · electronic medicines compendium (emc), UK

• ACE inhibitorsThere may be an increased risk of angioedema in patients concomitantly taking ACE inhibitors.electronic medicines compendium (emc), UK
• Thiazides, corticosteroids, thyroid products and sympathomimeticsThe hypoglycaemic effect of vildagliptin may be reduced by these active substances.electronic medicines compendium (emc), UK

• There are no adequate data in pregnant women and animal studies showed reproductive toxicity at high doses; because of the lack of human data it should not be used during pregnancy.International label, same formulation · electronic medicines compendium (emc), UK
• It is unknown whether vildagliptin is excreted in human milk (animal studies show excretion in milk); it should not be used during breast-feeding.International label, same formulation · electronic medicines compendium (emc), UK

• Vildagliptin: Selective DPP-4 inhibitor that increases endogenous GLP-1 and GIP.