سعر ايماكيوليت اكس ال 500 مجم 7 اقراص 2022

Immaculate XL clarithromycin 500 mg extended-release tablets (pack of 7), a macrolide antibacterial.

• Acute bacterial exacerbation of chronic bronchitis (H. influenzae, H. parainfluenzae, M. catarrhalis, S. pneumoniae)Population: AdultsDailyMed (U.S. National Library of Medicine)
• Acute maxillary sinusitisPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Community-acquired pneumoniaPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent in clinical trials: abdominal pain, diarrhea, nausea, vomiting and dysgeusia (taste disturbance).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to clarithromycin, erythromycin or any macrolide.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant cisapride, pimozide, ergotamine/dihydroergotamine, lomitapide, lovastatin, simvastatin or lurasidone; colchicine in patients with renal or hepatic impairment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• History of cholestatic jaundice or hepatic dysfunction associated with prior clarithromycin use.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Severe acute hypersensitivity reactions (anaphylaxis, SJS/TEN, DRESS): discontinue.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• QT prolongation: avoid in known QT prolongation, torsades de pointes, uncorrected hypokalemia/hypomagnesemia, significant bradycardia or with class IA/III antiarrhythmics.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Hepatotoxicity; serious reactions from interactions (colchicine, statins, calcium channel blockers); increased all-cause mortality one year or more after treatment in coronary artery disease; C. difficile-associated diarrhea; exacerbation of myasthenia gravis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• CYP3A substrates (e.g. carbamazepine)Clarithromycin inhibits CYP3A and may increase their concentrations and effects; use with caution, monitor levels and adjust doses.DailyMed (U.S. National Library of Medicine)
• Lovastatin, simvastatin, lomitapideContraindicated (myopathy/rhabdomyolysis; marked transaminase increases with lomitapide).DailyMed (U.S. National Library of Medicine)
• ColchicineContraindicated in renal or hepatic impairment; risk of colchicine toxicity.DailyMed (U.S. National Library of Medicine)

• Based on animal findings, not recommended in pregnant women except when no alternative therapy is appropriate; limited human data are insufficient to inform risk.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Clarithromycin: Macrolide that binds the 50S ribosomal subunit and inhibits bacterial protein synthesis.