سعر اندوميثاسين 25مجم 30 كبسولة 2022

Indomethacin 25 mg 30 capsules (Misr) (Misr Company for Pharmaceutical Industries, Egypt): indomethacin 25 mg oral capsules, an NSAID for rheumatic and musculoskeletal pain and inflammation.

• Moderate to severe rheumatoid arthritis including acute flares of chronic disease.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Moderate to severe ankylosing spondylitis.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Moderate to severe osteoarthritis.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (>=3%): headache, dizziness, dyspepsia and nausea.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to indomethacin or components; history of asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs; setting of CABG surgery.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased risk of serious cardiovascular thrombotic events (MI, stroke) and of serious gastrointestinal bleeding, ulceration and perforation, which can be fatal.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Other warnings: hepatotoxicity, hypertension, heart failure and oedema, renal toxicity and hyperkalaemia, anaphylaxis, serious skin reactions, DRESS, fetal toxicity, haematologic toxicity, CNS effects (headache, dizziness, depression) and ocular effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anticoagulants (e.g., warfarin), antiplatelets, SSRIs/SNRIsIncreased risk of serious bleeding.DailyMed (U.S. National Library of Medicine)

• NSAIDs can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction (oligohydramnios); limit dose and duration at about 20-30 weeks and avoid from about 30 weeks of gestation.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Indomethacin may be present in human milk; weigh benefits of breastfeeding against maternal need and potential infant effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Indomethacin: Inhibits cyclo-oxygenase and prostaglandin synthesis, producing anti-inflammatory, analgesic and antipyretic effects.