سعر انفاكافين 10مجم/مل فيال وريدي 3 مل 2026

Infacafin 10 mg/ml intravenous vial (3 ml): caffeine injection listed in Egypt under Inad Pharma as a methylxanthine CNS stimulant.

• Treatment of apnea of prematurity.Population: Preterm infantsDailyMed (U.S. National Library of Medicine)

• Events more frequent than placebo in the controlled trial included feeding intolerance, rash, sepsis, necrotizing enterocolitis, gastritis, gastrointestinal haemorrhage and others (small numbers).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any of the components.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Necrotizing enterocolitis: cases occurred in the pivotal trial (a causal relationship with methylxanthines is not established); monitor all treated preterm infants carefully for necrotizing enterocolitis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Apnea of prematurity is a diagnosis of exclusion: rule out or treat other causes (CNS disorders, lung disease, anaemia, sepsis, metabolic or cardiovascular abnormalities, obstructive apnea) before starting.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Use with caution in infants with seizure disorders (seizures reported in overdose) and in infants with cardiovascular disease (caffeine increases heart rate and cardiac output).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• CYP1A2 inhibitors (e.g. cimetidine, ketoconazole)May decrease caffeine elimination; lower caffeine doses may be needed.DailyMed (U.S. National Library of Medicine)
• CYP1A2 inducers (e.g. phenobarbital, phenytoin)May increase caffeine elimination; higher caffeine doses may be needed.DailyMed (U.S. National Library of Medicine)
• TheophyllineInterconversion between caffeine and theophylline occurs in preterm neonates; concurrent use is not recommended.DailyMed (U.S. National Library of Medicine)

• The US label states that concern for teratogenicity is not relevant when the product is given to infants; caffeine caused cleft palate and exencephaly in mice at high doses, and there are no adequate studies in pregnant women.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Caffeine: Caffeine is a methylxanthine CNS stimulant; its effects are mainly attributed to antagonism of adenosine receptors (the US label notes stimulation of the respiratory centre, increased minute ventilation and CO2 sensitivity).