سعر انوفيفين 400 مجم 20 قرص 2022

Innovifen 400 mg film-coated tablets (pack of 20): dexibuprofen, the active S(+)-enantiomer of ibuprofen, an NSAID for pain and inflammation, by Marcyrl Pharmaceutical Industries, Egypt.

• Pain and inflammation in osteoarthritis/arthrosis.Population: Adultselectronic medicines compendium (emc), UK
• Primary dysmenorrhoea (menstrual pain).Population: Adultselectronic medicines compendium (emc), UK
• Mild to moderate pain such as musculoskeletal pain, headache or toothache, and painful swelling and inflammation after injury.Population: Adultselectronic medicines compendium (emc), UK

• Hypersensitivity to dexibuprofen, other NSAIDs or excipients, or history of asthma, bronchospasm, rhinitis, nasal polyps, urticaria or angioedema triggered by aspirin/NSAIDs.International label, same formulation · electronic medicines compendium (emc), UK
• History of NSAID-related GI bleeding or perforation; active or recurrent peptic ulcer/haemorrhage; cerebrovascular or other active bleeding; active Crohn's disease or ulcerative colitis.International label, same formulation · electronic medicines compendium (emc), UK
• Severe heart failure, severe renal dysfunction (GFR <30 ml/min) or severely impaired hepatic function.International label, same formulation · electronic medicines compendium (emc), UK

• GI bleeding, ulceration and perforation (possibly fatal) can occur at any time; risk higher in the elderly and at higher doses. Avoid concomitant NSAIDs including COX-2 inhibitors; use the lowest effective dose for the shortest time.International label, same formulation · electronic medicines compendium (emc), UK
• NSAIDs may impair fertility reversibly and are not recommended in women attempting to conceive.International label, same formulation · electronic medicines compendium (emc), UK

• Other NSAIDs / aspirin (analgesic doses)Increased risk of GI ulceration and bleeding; avoid the combination.electronic medicines compendium (emc), UK
• Anticoagulants (e.g. warfarin)NSAIDs may enhance the effect of anticoagulants.electronic medicines compendium (emc), UK
• MethotrexateNSAIDs may increase methotrexate levels and toxicity.electronic medicines compendium (emc), UK

• Per the UK SmPC, short-term low-dose use may be compatible with breastfeeding; with longer or higher-dose use, early weaning should be considered.International label, same formulation · electronic medicines compendium (emc), UK

• Dexibuprofen: Non-selective cyclo-oxygenase inhibition reducing prostaglandin synthesis, giving analgesic, anti-inflammatory and antipyretic effects.