سعر ناليف 375 مجم 10 اقراص 2022

Naleve 375 mg enteric-coated tablets, pack of 10 (Sigma): oral naproxen 375 mg NSAID (propionic acid derivative).

• Signs and symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and polyarticular juvenile idiopathic arthritisPopulation: Adults; pediatric polyarticular JIA per US labelDailyMed (U.S. National Library of Medicine)

• Most frequent complaints are gastrointestinal (heartburn, abdominal pain, nausea, among others) in about 1-10% of patients in clinical trials.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to naproxen or any component; history of asthma, urticaria or other allergic-type reactions after aspirin or other NSAIDs; in the setting of coronary artery bypass graft (CABG) surgery.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased risk of serious cardiovascular thrombotic events (myocardial infarction, stroke) and of serious gastrointestinal bleeding, ulceration and perforation, which can be fatal; elderly patients and those with prior ulcer/GI bleeding are at greater risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Renal toxicity and hyperkalaemia; avoid in advanced renal disease unless benefits outweigh risks.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anticoagulants (e.g., warfarin), antiplatelets (e.g., aspirin), SSRIs and SNRIsIncreased risk of bleeding; monitor for signs of bleeding.DailyMed (U.S. National Library of Medicine)
• Low-dose aspirin (antiplatelet use)Naproxen may interfere with the antiplatelet effect of low-dose aspirin.DailyMed (U.S. National Library of Medicine)

• NSAIDs can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios; limit dose and duration between about 20 and 30 weeks and avoid from about 30 weeks of gestation.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• The naproxen anion is found in breast milk at about 1% of the maximum plasma concentration; weigh benefits of breastfeeding against the mother's need for naproxen.International label, same formulation · DailyMed (U.S. National Library of Medicine)

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