سعر ديكسافلابو 400 مجم 20 قرص مغلف 2022

Dexaflabu 400 mg film-coated tablets (20): dexibuprofen by Delta Pharma.

• Symptomatic treatment of osteoarthritis pain/inflammation, primary dysmenorrhoea, mild-to-moderate pain; short-term symptomatic rheumatoid arthritis when DMARDs not considered (UK SmPC)Population: Adults and children/adolescents from 8 years (UK SmPC)UK eMC / MHRA

• Hypersensitivity to dexibuprofen/NSAIDs/excipients; NSAID-precipitated asthma/rhinitis/urticaria; history of GI bleeding/perforation with NSAIDs; active/recurrent peptic ulcer; cerebrovascular or other active bleeding; active IBD; severe heart/renal/hepatic failure; from beginning of 6th month of pregnancy.International label, same formulation · UK eMC / MHRA

• Use lowest effective dose for shortest duration. GI bleeding/ulceration risk (higher in elderly). Cardiovascular risk may increase at high doses (1200 mg/day dexibuprofen analogous to high-dose ibuprofen). Avoid other NSAIDs/COX-2 inhibitors. SCARs reported — discontinue if suspected.International label, same formulation · UK eMC / MHRA

• Other NSAIDs / salicylatesMajorIncreased GI ulceration and bleeding risk; concomitant use not recommended. Management: Avoid combination.UK eMC / MHRA
• Anticoagulants (e.g. warfarin)MajorNSAIDs may enhance anticoagulant effect. Management: Monitor INR/bleeding time; adjust anticoagulant if needed.UK eMC / MHRA

• Contraindicated from the beginning of the 6th month of pregnancy. During 1st/2nd trimester use only if clearly necessary at lowest dose/shortest duration; from week 20 monitor for oligohydramnios/ductus constriction.International label, same formulation · UK eMC / MHRA

• Dexibuprofen: Non-selective COX inhibition reducing prostaglandin synthesis; analgesic, anti-inflammatory and antipyretic effects.