سعر انفيجا 3مجم 7 اقراص ممتدة المفعول 2026

Invega 3 mg: paliperidone 3 mg extended-release tablets, pack of 7 (Janssen-Cilag, distributed in Egypt by Soficopharm); atypical antipsychotic.

• SchizophreniaPopulation: Adults and adolescents 12-17 yearsDailyMed (U.S. National Library of Medicine)
• Schizoaffective disorder (monotherapy or adjunct to mood stabilisers/antidepressants)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to paliperidone, risperidone or any excipient (anaphylaxis and angioedema reported).International label, same product · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased mortality in elderly patients with dementia-related psychosis; not approved for this use.International label, same product · DailyMed (U.S. National Library of Medicine)
• Modest QTc prolongation: avoid with other QT-prolonging drugs and in congenital long QT syndrome or history of arrhythmia.International label, same product · DailyMed (U.S. National Library of Medicine)
• Neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes (hyperglycaemia, dyslipidaemia, weight gain), hyperprolactinaemia, orthostatic hypotension, leukopenia/agranulocytosis, seizures and GI obstruction risk with the non-deformable tablet.International label, same product · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4/P-gp inducers (e.g. carbamazepine)Carbamazepine decreased paliperidone exposure by about 37%; re-evaluate and increase dose if needed, and reduce on stopping the inducer.DailyMed (U.S. National Library of Medicine)
• Divalproex sodiumIncreased paliperidone Cmax and AUC by about 50%; adjust dose if necessary.DailyMed (U.S. National Library of Medicine)
• RisperidoneNot studied together; consider additive paliperidone exposure (paliperidone is the major active metabolite of risperidone).DailyMed (U.S. National Library of Medicine)

• Epidemiologic data have not established a drug-associated risk of major birth defects or miscarriage; untreated schizophrenia carries maternal risks; a pregnancy exposure registry exists.International label, same product · DailyMed (U.S. National Library of Medicine)
• Limited data show paliperidone in breast milk; sedation, failure to thrive, jitteriness and extrapyramidal symptoms reported in infants exposed to risperidone; weigh benefits and risks.International label, same product · DailyMed (U.S. National Library of Medicine)

English text not available for this section.