سعر ايفرزين 6مجم 24 قرص 2024

Ivermectin 6 mg oral tablets (Unipharma Co.), an avermectin antiparasitic agent.

• In strongyloidiasis studies: dizziness and pruritus (2.8%), diarrhoea and nausea (1.8%), and fatigue, abdominal pain, anorexia, constipation, vomiting, somnolence, vertigo, tremor, rash and urticaria (0.9% each). Post-marketing: hypotension, worsening asthma, toxic epidermal necrolysis, Stevens-Johnson syndrome, seizures, hepatitis and raised liver enzymes/bilirubin.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• In onchocerciasis, killing of microfilariae can cause Mazzotti-type cutaneous/systemic and ophthalmological reactions; patients heavily infected with Loa loa may rarely develop serious or fatal encephalopathy, so people with significant exposure to Loa loa-endemic areas of West or Central Africa need pre-treatment assessment and careful follow-up.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Neurotoxicity (somnolence, stupor, coma, confusion, disorientation, death) has been reported, including in patients without onchocerciasis or Loa loa; it generally resolved with supportive care and stopping ivermectin.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• WarfarinRare post-marketing reports of increased INR when ivermectin was given with warfarin.DailyMed (U.S. National Library of Medicine)

• Teratogenic in mice, rats and rabbits only at or near maternotoxic doses (cleft palate; clubbed forepaws in rabbits); no adequate studies in pregnant women; the US label says ivermectin should not be used during pregnancy since safety has not been established.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Excreted in human milk in low concentrations; treat breastfeeding mothers only when the risk of delayed maternal treatment outweighs the possible risk to the newborn.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ivermectin: Avermectin antiparasitic: binds with high affinity to glutamate-gated chloride channels in invertebrate nerve and muscle cells, increasing chloride permeability, hyperpolarising the cells and causing paralysis and death of the parasite.