سعر كينوموكسي 400مجم 5 اقراص 2025

Moxifloxacin 400 mg film-coated tablets, 5 per pack (Kinomoxi, Al Esraa Pharmaceutical Optima, Egypt); fluoroquinolone antibacterial.

• Community-acquired pneumonia, skin and skin structure infections, complicated intra-abdominal infections, plague, acute bacterial sinusitis and acute bacterial exacerbation of chronic bronchitis caused by susceptible bacteria (US label).Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (at least 3%): nausea, diarrhoea, headache and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to moxifloxacin or any other quinolone.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones are associated with disabling and potentially irreversible serious reactions (tendinitis and tendon rupture, peripheral neuropathy, central nervous system effects) and may exacerbate myasthenia gravis; discontinue at the first sign and avoid in patients with myasthenia gravis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Because of serious adverse reactions, reserve moxifloxacin for acute bacterial sinusitis and acute bacterial exacerbation of chronic bronchitis in patients with no alternative treatment options.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• QT interval prolongation can occur; avoid in patients with known QT prolongation, uncorrected hypokalaemia and with class IA or class III antiarrhythmics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids, sucralfate, multivalent cations (iron, zinc, magnesium, aluminium)Reduce moxifloxacin absorption; take moxifloxacin 4 hours before or 8 hours after these products.DailyMed (U.S. National Library of Medicine)
• WarfarinEnhanced anticoagulant effect; monitor prothrombin time/INR.DailyMed (U.S. National Library of Medicine)
• Class IA and class III antiarrhythmicsAdditive QT prolongation; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• No human data establish a drug-associated risk; animal studies at maternally toxic doses showed fetal loss, lower neonatal weight and skeletal variations, so moxifloxacin may cause fetal harm; advise pregnant women of the potential risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Moxifloxacin: Bactericidal; inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes needed for bacterial DNA replication, transcription and repair.