سعر كوناكيون اطفال 2مجم/0.2 مل 5 امبولات للحقن العضلي 2022

Konakion MM Paediatric phytomenadione (vitamin K1) 2 mg/0.2 ml mixed-micelle solution, 5 ampoules for IM, IV or oral use (Roche).

• Prophylaxis and treatment of vitamin K deficiency bleeding (VKDB) in neonates and infants; on haematologist advice, antidote to coumarin anticoagulants in infants and children (UK SmPC, same product name and strength).Population: Neonates, infants and childrenelectronic medicines compendium (emc)

• Anaphylactoid reactions after IV injection; local injection-site irritation; rarely severe injection-site reactions including inflammation, atrophy and necrosis.International label, same product · electronic medicines compendium (emc)

• Hypersensitivity to phytomenadione or any excipient.International label, same product · electronic medicines compendium (emc)

• Do not use if the ampoule contents are turbid or separated. Parenteral use in premature babies under 2.5 kg may increase the risk of kernicterus. Infants with cholestatic disease must receive it IM or IV (impaired oral absorption). As a coumarin antidote it must be given IV (IM may cause significant bleeding). Care is needed with weight-based dosing (tenfold errors are common).International label, same product · electronic medicines compendium (emc)

• Coumarin anticoagulants (e.g. warfarin)Antagonises coumarin anticoagulants; no other significant interactions known.electronic medicines compendium (emc)

• Phytomenadione (vitamin K1): Cofactor for the hepatic synthesis of vitamin K-dependent clotting factors (II, VII, IX, X); antagonises coumarin anticoagulants.