سعر كونازول 2% كريم 15 جم 2022

Konazole ketoconazole 2% cream, 15 g (Alfacure, Egypt); topical imidazole antifungal.

• Topical treatment of tinea corporis, tinea cruris and tinea pedis (Trichophyton rubrum, T. mentagrophytes, Epidermophyton floccosum), tinea (pityriasis) versicolor (Malassezia furfur), cutaneous candidiasis and seborrhoeic dermatitis (US label, ketoconazole 2% cream).DailyMed (U.S. National Library of Medicine)

• In trials 5.0% reported side effects, mainly severe irritation, pruritus and stinging; rare contact dermatitis reported post-marketing (ketoconazole or excipients such as sodium sulfite or propylene glycol).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to ketoconazole or any excipient of the formulation.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Not for ophthalmic use. The US cream contains sodium sulfite, which may cause allergic-type reactions including anaphylaxis and asthmatic episodes in susceptible people (excipients of the Egyptian cream not verified). Discontinue if sensitivity or chemical irritation occurs; the systemic effects of oral ketoconazole have not been seen with topical use.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; use only if the potential benefit justifies the potential risk to the fetus. Oral ketoconazole was teratogenic in rats at 80 mg/kg/day.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Ketoconazole: Inhibits fungal ergosterol synthesis (lanosterol 14-alpha-demethylation), damaging the fungal cell membrane.