سعر نيزوديرم 2% كريم 15 جم 2024

Nizoderm 2% ketoconazole cream (Unipharma, Egypt), 15 g; topical imidazole antifungal.

• Tinea corporis, tinea cruris and tinea pedis caused by Trichophyton rubrum, T. mentagrophytes and Epidermophyton floccosumDailyMed (U.S. National Library of Medicine)
• Tinea (pityriasis) versicolor caused by Malassezia furfurDailyMed (U.S. National Library of Medicine)
• Cutaneous candidiasis caused by Candida spp.DailyMed (U.S. National Library of Medicine)

• In trials 5.0% reported side effects, mainly severe irritation, pruritus and stinging; one painful allergic reaction; rare post-marketing contact dermatitis (ketoconazole, sodium sulfite or propylene glycol).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to ketoconazole or to any excipient of the formulation.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Not for ophthalmic use. The US cream contains sodium sulfite, which may cause allergic-type reactions including asthmatic episodes in susceptible people (Egyptian excipients not verified). Discontinue if sensitivity or chemical irritation occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Oral ketoconazole was teratogenic in rats at 80 mg/kg/day (possibly related to maternal toxicity); no adequate studies in pregnant women; use in pregnancy only if benefit justifies risk. No systemic absorption was detected after topical application in volunteers.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether topical use gives enough systemic absorption to reach breast milk; decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Ketoconazole: Impairs synthesis of ergosterol, a vital component of fungal cell membranes, altering membrane permeability (US ketoconazole cream label).