سعر كيوبان 100مجم 5 اقماع لبوس 2023

Ketoprofen 100 mg rectal suppositories (5 per pack), a propionic-acid NSAID with analgesic, antipyretic and anti-inflammatory activity.

• Long-term symptomatic treatment of chronic inflammatory rheumatism (e.g. rheumatoid arthritis, ankylosing spondylitis) and some painful, disabling osteoarthritis.Population: Adults and adolescents from 15 yearsANSM (Agence nationale de securite du medicament et des produits de sante)
• Short-term symptomatic treatment of acute flares: periarticular rheumatism (tendinitis, bursitis, shoulder periarthritis), microcrystalline arthritis, osteoarthritis, low back pain, radicular pain and benign acute post-traumatic musculoskeletal conditions.Population: Adults and adolescents from 15 yearsANSM (Agence nationale de securite du medicament et des produits de sante)

• Most frequent effects are gastrointestinal (peptic ulcer, perforation or GI bleeding, sometimes fatal, especially in the elderly; nausea, vomiting, diarrhoea, dyspepsia, abdominal pain). Oedema, hypertension and heart failure have been reported with NSAIDs; very rarely bullous reactions (Stevens-Johnson, Lyell). A small increase in arterial thrombotic risk is possible at high doses/long term.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)

• Hypersensitivity to ketoprofen or excipients; history of bronchospasm, asthma, rhinitis, urticaria or other allergic reactions to ketoprofen, aspirin or other NSAIDs.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)
• Active peptic ulcer or history of GI bleeding, ulceration or perforation; active GI, cerebrovascular or other bleeding.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)
• Severe hepatic, renal or cardiac failure.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)

• Risk of fetal death even after a single dose from 24 weeks of amenorrhoea (constriction of the ductus arteriosus, oligohydramnios); risk of neonatal renal failure and pulmonary hypertension.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)
• Avoid combination with other NSAIDs including COX-2 inhibitors; use the lowest effective dose for the shortest duration to limit GI and cardiovascular risks.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)
• Patients with asthma associated with chronic rhinitis, sinusitis and/or nasal polyps are at higher risk of asthma attacks or bronchospasm.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)

• Hyperkalaemia-promoting drugs (potassium salts, potassium-sparing diuretics, ACE inhibitors, angiotensin II antagonists, heparins, ciclosporin, tacrolimus, trimethoprim)Combination with ketoprofen increases the risk of hyperkalaemia.ANSM (Agence nationale de securite du medicament et des produits de sante)
• Other NSAIDs including COX-2 inhibitorsConcomitant use should be avoided.ANSM (Agence nationale de securite du medicament et des produits de sante)

• Contraindicated from the start of the 6th month (24 weeks of amenorrhoea), even as a single dose; before 24 weeks, use only if absolutely necessary at the lowest dose for the shortest time.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)
• NSAIDs pass into breast milk; not recommended during breastfeeding.International label, same formulation · ANSM (Agence nationale de securite du medicament et des produits de sante)

• Ketoprofen: Inhibits prostaglandin synthesis, giving peripheral and central analgesic, antipyretic and anti-inflammatory effects and short-lived inhibition of platelet function (ANSM RCP 5.1).