سعر لازيكس 20مجم 3 امبولات 20 مجم/2 مل 2024

Furosemide 20 mg/2 ml solution for intramuscular or intravenous injection, pack of 3 ampoules, by Sedico > Sanofi (Egypt); loop diuretic.

• Oedema associated with congestive heart failure, cirrhosis of the liver and renal disease including the nephrotic syndrome, when a rapid onset of diuresis is desired or oral therapy is not feasible.Population: Adults and pediatric patientsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy in acute pulmonary oedema.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Reported reactions include fluid and electrolyte depletion (hypokalaemia, hyponatraemia, hypochloraemic alkalosis), dehydration, orthostatic hypotension, hyperglycaemia, hyperuricaemia, tinnitus and hearing impairment, pancreatitis, jaundice, anorexia, nausea, diarrhoea, blood dyscrasias (aplastic anaemia, thrombocytopenia, agranulocytosis), photosensitivity, rash, severe cutaneous reactions, vasculitis, interstitial nephritis, dizziness, headache and muscle spasm.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anuria; history of hypersensitivity to furosemide.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Excessive diuresis may cause fluid, electrolyte and metabolic abnormalities (hypovolaemia, hypokalaemia, hyponatraemia, metabolic alkalosis, hyperglycaemia, hyperuricaemia); in cirrhosis sudden shifts may precipitate hepatic encephalopathy.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• May worsen renal function (including acute kidney injury) through excessive diuresis; monitor and interrupt or reduce dose as needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Ototoxicity (tinnitus, reversible or irreversible hearing impairment) is associated with rapid injection, severe renal impairment, high doses and concomitant ototoxic drugs.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Aminoglycoside antibiotics and other ototoxic drugs (e.g. ethacrynic acid)Increased risk of ototoxicity, especially with impaired renal function; avoid the combination except in life-threatening situations.DailyMed (U.S. National Library of Medicine)
• LithiumFurosemide reduces lithium renal clearance and raises the risk of lithium toxicity; generally do not combine.DailyMed (U.S. National Library of Medicine)
• ACE inhibitors and angiotensin II receptor blockersMay cause severe hypotension and deterioration of renal function, including renal failure; dose interruption or reduction may be needed.DailyMed (U.S. National Library of Medicine)

• Available published data with furosemide in pregnancy have not identified a drug-associated risk of major birth defects or miscarriage; animal studies showed fetal and maternal toxicity. Monitor fetal growth because of the potential for altered fetal fluid and electrolyte balance.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Furosemide is present in human milk; diuretics may suppress lactation. Weigh breastfeeding benefits against the mother's need for the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Furosemide: Loop diuretic that inhibits the Na+/K+/2Cl- co-transporter in the thick ascending limb of the loop of Henle, inhibiting sodium and chloride reabsorption and causing a rapid, potent diuresis.