سعر اميرون 150مجم/3مل 6 امبولات وريد 2022

Amiodarone 150 mg/3 ml (50 mg/ml) solution for intravenous use in ampoules (Amiron, Sedico, Egypt), a class III antiarrhythmic; pack of 6 ampoules.

• Initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and haemodynamically unstable ventricular tachycardia refractory to other therapy; also for VT/VF patients who need amiodarone but cannot take it orally. Use acutely until arrhythmias are stabilised, then transfer to oral therapy as appropriate.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypotension (16%) is the most common adverse reaction with intravenous amiodarone; bradycardia/AV block, liver enzyme elevations and injection-site reactions also occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to any component, including iodine.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cardiogenic shock.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Marked sinus bradycardia.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypotension is the most common adverse reaction (16% in trials), related to infusion rate; treat by slowing the infusion and, if needed, vasopressors, inotropes and volume expansion.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Bradycardia and AV block (4.9% in trials); slow or stop the infusion; pacing may be needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hepatic injury: enzyme elevations are common; monitor liver enzymes and consider dose reduction or withdrawal if elevations are significant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• WarfarinIncreased anticoagulant response (INR) is almost always seen and can cause serious bleeding; reduce the warfarin dose and monitor INR closely.DailyMed (U.S. National Library of Medicine)
• Digoxin, beta-blockers, verapamil, diltiazem, ivabradine, clonidinePotentiate electrophysiological and haemodynamic effects, causing bradycardia, sinus arrest and AV block; monitor heart rate.DailyMed (U.S. National Library of Medicine)
• Sofosbuvir (alone or with other hepatitis C antivirals)Postmarketing symptomatic bradycardia, some requiring pacemaker insertion and at least one fatal.DailyMed (U.S. National Library of Medicine)

• Amiodarone and desethylamiodarone cross the placenta. Reported risks include neonatal bradycardia, QT prolongation and ventricular extrasystoles, neonatal hypothyroidism (with or without goitre), neonatal hyperthyroxinaemia and neurodevelopmental abnormalities.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Amiodarone and desethylamiodarone are excreted in human milk, which could expose the infant to a significant dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Amiodarone: Prolongs the cardiac action potential and refractoriness (class III effect) by blocking myocardial potassium channels; also blocks sodium channels at rapid rates, has non-competitive antisympathetic action and slows nodal conduction (class I, II and IV-like effects).