سعر ليفوكتيفان 5مجم 30 قرص 2024

Film-coated tablet containing levocetirizine 5 mg, pack of 30 film-coated tablets, by Egpi > glenmark pharmaceuticals (Egypt); H1-antihistamine (antiallergic).

• Treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 years and older (tablet; younger children use the oral solution).Population: Adults and children 6 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (12 years and older): somnolence, nasopharyngitis, fatigue, dry mouth and pharyngitis; children 6-12 years: pyrexia, somnolence, cough and epistaxis; children 1-5 years: pyrexia, diarrhoea, vomiting and otitis media.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to levocetirizine, cetirizine or any ingredient (reactions from urticaria to anaphylaxis).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• End-stage renal disease (creatinine clearance below 10 mL/min) and patients undergoing haemodialysis; children 6 months to 11 years with impaired renal function.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Somnolence, fatigue and asthenia may occur; avoid hazardous activities requiring full alertness such as driving, and avoid alcohol or other CNS depressants.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Urinary retention has been reported; use with caution when predisposed (e.g. spinal cord lesion, prostatic hyperplasia) and discontinue if it occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• New-onset pruritus may occur within a few days after stopping long-term use; symptoms may improve with restarting or tapering.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• RitonavirRitonavir increased cetirizine AUC by about 42% (studies with racemic cetirizine).DailyMed (U.S. National Library of Medicine)
• TheophyllineA 400 mg theophylline dose caused a small (~16%) decrease in cetirizine clearance; higher theophylline doses could have a greater effect.DailyMed (U.S. National Library of Medicine)
• Alcohol and other CNS depressantsAdditional reduction in alertness and CNS performance; avoid concurrent use.DailyMed (U.S. National Library of Medicine)

• Available published and postmarketing data on levocetirizine in pregnancy are insufficient to identify a drug-associated risk of miscarriage, birth defects or adverse maternal or fetal outcomes; no fetal harm in rats and rabbits at high multiples of the human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on levocetirizine in human milk, but cetirizine has been reported in human breast milk; weigh the benefits of breastfeeding against the mother's need for the drug and possible effects on the child.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Levocetirizine: Levocetirizine, the active enantiomer of cetirizine, is an antihistamine whose principal effects are mediated via selective inhibition of H1 receptors (US label).