سعر لينكوسين 600مجم /2مل عضل/وريد 3 امبول 2022

Lincomycin 600 mg/2 ml (300 mg/ml) injection ampoules for intramuscular or intravenous use, a lincosamide antibiotic for serious Gram-positive infections.

• Serious infections due to susceptible strains of streptococci, pneumococci and staphylococci, reserved for penicillin-allergic patients or patients for whom a penicillin is inappropriate.Population: Adults and children over 1 monthDailyMed (U.S. National Library of Medicine)

• Gastrointestinal: diarrhoea, nausea, vomiting, glossitis, stomatitis, abdominal pain, anal pruritus; skin: rash, urticaria, pruritus and severe cutaneous reactions; blood: neutropenia, leukopenia, agranulocytosis, thrombocytopenic purpura, aplastic anaemia, pancytopenia; jaundice and raised transaminases; renal impairment, oliguria, proteinuria; hypotension, thrombophlebitis and cardio-respiratory arrest (with too-rapid IV use); vertigo, tinnitus, headache, dizziness, somnolence; injection-site pain, induration and sterile abscess.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to lincomycin or clindamycin.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: Clostridioides difficile-associated diarrhoea, ranging from mild diarrhoea to fatal colitis, may occur even more than two months after treatment; reserve lincomycin for serious infections where less toxic antimicrobials are inappropriate and do not use it for non-bacterial infections such as most upper respiratory tract infections.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Severe hypersensitivity reactions, including anaphylaxis and severe cutaneous adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis, erythema multiforme); discontinue and treat appropriately.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cerebrospinal fluid concentrations may be inadequate for the treatment of meningitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Neuromuscular blocking agentsLincomycin has neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; use with caution.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; use during pregnancy only if clearly needed. Lincomycin crosses the placenta (cord serum about 25% of maternal serum); experience in 345 obstetric patients showed no ill effects related to pregnancy, and no teratogenicity was seen in rats.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Lincomycin appears in human milk at 0.5 to 2.4 mcg/mL; because of potential serious adverse reactions in nursing infants, decide whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Lincomycin (as hydrochloride): Lincosamide antibacterial: binds the 23S RNA of the bacterial 50S ribosomal subunit and inhibits protein synthesis; predominantly bacteriostatic. Cross-resistance with clindamycin.