سعر ليبتيتام اكس ار 1000مجم 20 قرص 2024

Levetiracetam 1000 mg extended-release film-coated tablets, 20 per pack (Liptitam XR, Organopharma, Egypt); antiepileptic.

• Adjunctive therapy for partial-onset seizures in patients 12 years of age and older.Population: Patients 12 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (incidence at least 5% more than placebo): somnolence and irritability.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to levetiracetam; anaphylaxis and angioedema have occurred.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Behavioural abnormalities and psychotic symptoms (including irritability and aggression) may occur; monitor for psychiatric signs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs increase the risk of suicidal thoughts or behaviour; monitor for new or worsening depression or unusual mood changes.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Somnolence, fatigue and coordination difficulties: patients should not drive or operate machinery until they know how the drug affects them.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Prolonged experience with levetiracetam in pregnancy has not identified a drug-associated risk of major birth defects or miscarriage; plasma levels may fall during pregnancy, especially in the third trimester, so close monitoring is recommended through the postpartum period. A pregnancy exposure registry (NAAED) exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Levetiracetam is excreted in human milk; weigh the benefits of breastfeeding against the clinical need for the drug and possible effects on the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Levetiracetam: The precise mechanism of the antiepileptic effect is unknown; levetiracetam binds the synaptic vesicle protein SV2A, which is thought to be involved in regulating vesicle exocytosis, and binding affinity correlated with antiseizure potency in animal models.