سعر مازيمال 200مجم سي ار 20 قرص 2026

Carbamazepine 200 mg controlled-release film-coated tablets (20 per pack) by Unipharma, Egypt; an antiepileptic (carboxamide).

• Epilepsy: partial seizures with complex symptomatology, generalized tonic-clonic seizures and mixed seizure patterns (absence seizures are not controlled).Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Pain associated with true trigeminal neuralgia; not a simple analgesic for trivial aches or pains.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent, especially early in therapy: dizziness, drowsiness, unsteadiness, nausea and vomiting; the most severe reactions involve the blood-forming system, skin, liver and cardiovascular system.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• History of bone marrow depression; hypersensitivity to carbamazepine or to tricyclic compounds; use with MAO inhibitors (stop MAOIs at least 14 days before); coadministration with nefazodone.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: serious and sometimes fatal dermatologic reactions (TEN, SJS), strongly associated with HLA-B*1502 in patients of Asian ancestry; screen at-risk patients before starting.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: aplastic anemia and agranulocytosis; obtain complete pretreatment hematological testing and monitor patients with low or decreasing white cell or platelet counts.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Other label warnings include DRESS/multiorgan hypersensitivity, HLA-A*3101-associated hypersensitivity, and suicidal behavior and ideation with antiepileptic drugs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• MAO inhibitorsUse with MAO inhibitors is not recommended; discontinue MAOIs at least 14 days before carbamazepine.DailyMed (U.S. National Library of Medicine)
• NefazodoneCarbamazepine lowers nefazodone and its active metabolite to subtherapeutic levels; coadministration is contraindicated.DailyMed (U.S. National Library of Medicine)

• Carbamazepine can cause fetal harm; epidemiological data suggest an association with congenital malformations including spina bifida, and developmental delays have been reported.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Carbamazepine and its epoxide pass into breast milk (milk:plasma about 0.4 and 0.5); decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Carbamazepine: Prolongs the inactivated state of voltage-gated neuronal sodium channels, reducing high-frequency neuronal firing.