سعر ميبادرين 250مجم فيال 2022

Cefradine (cephradine) 250 mg vial for injection (Chemipharm, Egypt), a first-generation cephalosporin antibiotic; one vial per pack.

• Undesirable effects are uncommon and mainly mild, essentially gastrointestinal disturbances (diarrhoea, nausea, vomiting, heartburn, abdominal discomfort, glossitis) and occasional hypersensitivity. Also listed: antibiotic-associated colitis, candidiasis/vaginitis, eosinophilia and blood disorders (thrombocytopenia, leucopenia, agranulocytosis, aplastic and haemolytic anaemia), fever, arthralgia, serum-sickness-like reactions, anaphylaxis, headache, dizziness, transient hepatitis and cholestatic jaundice, rashes, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis and reversible interstitial nephritis.General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)

• Hypersensitivity to cefradine or to any of the excipients.General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)

• Use with caution in patients with a history of penicillin hypersensitivity (partial cross-allergenicity between penicillins and cephalosporins).General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)
• Renal impairment: cefradine is excreted by the kidneys and dosage must be reduced in patients with impaired renal function (the UK SmPC gives a creatinine-clearance based schedule).General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)
• Prolonged use of antibiotics may result in overgrowth of non-susceptible organisms (antibiotic-associated colitis and candidiasis are listed undesirable effects). The UK capsules contain lactose (patients with galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not take them; excipients of the Egyptian products not known).General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)
• May cause a false-positive reaction for glucose in urine with copper reduction tests (Benedict's or Fehling's solution, Clinitest), but not with enzyme-based tests.General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)

• Loop diuretics (e.g. furosemide)Concomitant use with potent diuretics may increase the risk of nephrotoxicity.electronic medicines compendium (emc), archived copy (Internet Archive)
• ProbenecidProbenecid reduces renal excretion of cefradine, increasing and prolonging its plasma concentrations.electronic medicines compendium (emc), archived copy (Internet Archive)

• Safety in pregnancy has not been established; as with other drugs, avoid in pregnancy, especially during the first trimester, unless considered essential.General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)
• Cefradine is excreted in breast milk; use with caution in breast-feeding women.General active-ingredient information · electronic medicines compendium (emc), archived copy (Internet Archive)

• Cefradine (cephradine): Broad-spectrum bactericidal first-generation cephalosporin active against Gram-positive and Gram-negative bacteria, including penicillinase-producing staphylococci (UK SmPC).