سعر ميتولانيكس 5مجم 10 اقراص 2023

Metolazone 5 mg tablets (Metolanix; Marcyrl, marketed by Arabcomed-Egypt); pack of 10 tablets (1 strip).

• Salt and water retention including oedema of congestive heart failure and of renal disease (including nephrotic syndrome and diminished renal function); hypertension alone or with other antihypertensives.Population: AdultsDailyMed (U.S. NLM)

• Usually well tolerated; reported reactions include chest discomfort, orthostatic hypotension, volume depletion, palpitations, syncope, dizziness, drowsiness, neuropathy and electrolyte disturbances.International label, same formulation · DailyMed (U.S. NLM)

• Anuria; hepatic coma or precoma; hypersensitivity to metolazone.International label, same formulation · DailyMed (U.S. NLM)

• Rapid onset of severe hyponatraemia and/or hypokalaemia has rarely been reported after initial doses; hypokalaemia may cause weakness, cramps and arrhythmias, especially in digitalised patients.International label, same formulation · DailyMed (U.S. NLM)
• Do not interchange Zaroxolyn-type metolazone tablets with Mykrox (rapidly available) formulations; they are not therapeutically equivalent at the same doses.International label, same formulation · DailyMed (U.S. NLM)
• Cross-allergy may occur in patients allergic to sulfonamide-derived drugs, thiazides or quinethazone.International label, same formulation · DailyMed (U.S. NLM)

• LithiumDiuretics reduce renal lithium clearance with high risk of lithium toxicity; generally avoid.DailyMed (U.S. NLM)
• FurosemideUnusually large or prolonged fluid and electrolyte losses may occur.DailyMed (U.S. NLM)
• Digitalis glycosidesDiuretic-induced hypokalaemia increases myocardial sensitivity to digitalis; serious arrhythmias may result.DailyMed (U.S. NLM)

• Routine diuretic use in otherwise healthy pregnant women is inappropriate; use only when oedema is due to pathologic causes.International label, same formulation · DailyMed (U.S. NLM)
• Metolazone appears in breast milk; decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. NLM)

• Metolazone: Inhibits sodium reabsorption mainly at the cortical diluting site and proximal convoluted tubule, increasing sodium and chloride excretion.