سعر ميكتونورم اكس ال 30 مجم 28 قرص مغطي بالسكر 2026

Propiverine hydrochloride 30 mg tablets (Apogepha) listed in Egypt as "XL" and sugar-coated; pack of 28. The modified-release nature of this product was not confirmed by an official leaflet.

• Very common: dry mouth. Common: headache, accommodation disorder, visual impairment, constipation, abdominal pain, dyspepsia, fatigue. Liver enzymes should be monitored during long-term therapy.General active-ingredient information · Health Products Regulatory Authority (HPRA), Ireland

• Hypersensitivity; bowel obstruction; significant bladder outflow obstruction where urinary retention may be anticipated; myasthenia gravis; intestinal atony; severe ulcerative colitis; toxic megacolon; uncontrolled angle-closure glaucoma; moderate or severe hepatic impairment; tachyarrhythmias.General active-ingredient information · Health Products Regulatory Authority (HPRA), Ireland

• Use with caution in autonomic neuropathy and renal or hepatic impairment; may aggravate severe heart failure, prostatic enlargement, hiatus hernia with reflux oesophagitis, arrhythmia and tachycardia; may precipitate acute angle-closure glaucoma; exclude renal, cardiac and organic bladder causes of frequency before treatment.General active-ingredient information · Health Products Regulatory Authority (HPRA), Ireland
• May cause drowsiness and blurred vision, which can impair driving and use of machines.General active-ingredient information · Health Products Regulatory Authority (HPRA), Ireland

• Tricyclic antidepressants, benzodiazepines, systemic anticholinergics, amantadine, neuroleptics, beta-agonistsEffects increased when combined with these drugs.Health Products Regulatory Authority (HPRA), Ireland
• Cholinergic drugsEffects of propiverine decreased.Health Products Regulatory Authority (HPRA), Ireland
• IsoniazidReduced blood pressure in patients treated with isoniazid.Health Products Regulatory Authority (HPRA), Ireland
• Prokinetics (e.g. metoclopramide)Effect of prokinetics may be decreased.Health Products Regulatory Authority (HPRA), Ireland

• No data in pregnant women; animal studies showed reproductive toxicity; not recommended during pregnancy.General active-ingredient information · Health Products Regulatory Authority (HPRA), Ireland
• Unknown whether excreted in human milk (excreted in animal milk); a decision is needed whether to stop breastfeeding or the medicine.General active-ingredient information · Health Products Regulatory Authority (HPRA), Ireland

• Propiverine hydrochloride: Inhibits calcium influx and modulates intracellular calcium in bladder smooth muscle and blocks muscarinic receptors, relaxing the detrusor (Irish Detrunorm SmPC, section 5.1).