سعر مينوفيللين اس. ار. 300مجم 30 قرص 2024

Theophylline 300 mg sustained-release tablets (Minophylline S.R.; Alexandria Co. for Pharmaceuticals), pack of 30 tablets.

• Treatment of the symptoms and reversible airflow obstruction of chronic asthma and other chronic lung diseases (e.g. emphysema, chronic bronchitis).Population: Adults and children aged 6 years and olderDailyMed (U.S. NLM)

• At peak serum levels below 20 mcg/mL, mainly transient caffeine-like effects (nausea, vomiting, headache, insomnia); above 20 mcg/mL, persistent vomiting, cardiac arrhythmias and intractable seizures that can be lethal.International label, equivalent formulation · DailyMed (U.S. NLM)

• History of hypersensitivity to theophylline or other components of the product.International label, equivalent formulation · DailyMed (U.S. NLM)

• Use with extreme caution in active peptic ulcer disease, seizure disorders and cardiac arrhythmias (not bradyarrhythmias).International label, equivalent formulation · DailyMed (U.S. NLM)
• Several factors reduce theophylline clearance (e.g. infancy or age over 60 years, prolonged fever, congestive heart failure, cor pulmonale, sepsis, smoking cessation and interacting drugs); if the daily dose is not reduced, severe and potentially fatal toxicity can occur.International label, equivalent formulation · DailyMed (U.S. NLM)

• Drugs that inhibit theophylline metabolism (e.g. cimetidine, erythromycin, tacrine)Raise theophylline levels; reduce the dose and monitor serum concentrations.DailyMed (U.S. NLM)
• Drugs that induce theophylline metabolism (e.g. carbamazepine, rifampin)Lower theophylline levels; stopping them can cause toxicity; monitor serum concentrations.DailyMed (U.S. NLM)

• No adequate well-controlled studies in pregnant women; use only if the potential benefit justifies the potential risk to the fetus.International label, equivalent formulation · DailyMed (U.S. NLM)
• Excreted into breast milk at about the maternal serum concentration; may cause irritability or other signs of mild toxicity in nursing infants.International label, equivalent formulation · DailyMed (U.S. NLM)

• Theophylline: Relaxes bronchial smooth muscle and suppresses airway responses to stimuli (phosphodiesterase inhibition and adenosine receptor antagonism).