سعر مينوفيللين ان 2.5% 5 امبول حقن وريدي 2024

Aminophylline (theophylline ethylenediamine) 2.5% solution for IV use, box of 5 ampoules (Minophylline-N, Alexandria). Ampoule volume not stated in the Egyptian price directories opened.

• Adjunct to inhaled beta-2 agonists and systemic corticosteroids for acute exacerbations of symptoms and reversible airflow obstruction associated with asthma and other chronic lung diseases (e.g. emphysema, chronic bronchitis).Population: Adults (acute exacerbations)DailyMed (US National Library of Medicine)

• At concentrations <20 mcg/mL mainly transient caffeine-like effects (nausea, vomiting, headache, insomnia); higher levels: persistent vomiting, cardiac arrhythmias, intractable seizures.International label, same formulation · DailyMed (US National Library of Medicine)

• Hypersensitivity to theophylline or other product components including ethylenediamine.International label, same formulation · DailyMed (US National Library of Medicine)

• Narrow therapeutic index: toxicity risk rises when serum theophylline exceeds about 20 mcg/mL (persistent vomiting, arrhythmias, seizures that can be lethal). Monitor serum concentrations.International label, same formulation · DailyMed (US National Library of Medicine)

• Drugs that alter theophylline clearance (e.g. CYP1A2 inhibitors/inducers)Theophylline has numerous pharmacokinetic interactions that raise or lower serum concentrations; check interacting drugs before and during IV therapy.DailyMed (US National Library of Medicine)

• No adequate well-controlled studies in pregnant women; animal data incomplete. Use only if clearly needed with monitoring.International label, same formulation · DailyMed (US National Library of Medicine)

• Aminophylline: Relaxes airway smooth muscle (bronchodilation) and suppresses airway responsiveness to stimuli; bronchodilation is thought to be mediated by inhibition of phosphodiesterase isozymes PDE III and, to a lesser extent, PDE IV (US label; mechanisms not known with certainty).