سعر ميرينا 20 مكجم/24 ساعة 52 مجم levonorgestrel 2026

Mirena T-shaped intrauterine system containing 52 mg levonorgestrel with average in vivo release ~20 mcg/24 hours (first year), for contraception and idiopathic menorrhagia.

• Contraception (effective for up to 8 years).Population: Women of fertile ageMHRA / eMC (Bayer plc)
• Idiopathic menorrhagia (effective for up to 5 years; remove/replace by 8 years).Population: Women with idiopathic menorrhagiaMHRA / eMC (Bayer plc)
• Protection from endometrial hyperplasia during oestrogen replacement therapy (remove no later than 4 years).Population: Women on oestrogen HRTMHRA / eMC (Bayer plc)

• Very common: uterine/vaginal bleeding including spotting, oligomenorrhoea, amenorrhoea. Common: ovarian cysts, pelvic/abdominal pain, headache, acne, breast pain/tenderness, expulsion.International label, same product · MHRA / eMC (Bayer plc)

• Known/suspected pregnancy; hormone-sensitive tumours including breast cancer; current/recurrent PID; cervicitis or current genital infection; postpartum endometritis/infected abortion in past 3 months; cervical dysplasia; uterine/cervical malignancy; undiagnosed abnormal genital bleeding; uterine cavity distortion; acute/severe liver disease or liver tumour; hypersensitivity.International label, same product · MHRA / eMC (Bayer plc)

• Insert only by trained professionals. Risk of uterine perforation (higher if breastfeeding or ≤36 weeks postpartum). Does not protect against STIs/HIV. Counsel on expulsion, pelvic infection, ectopic pregnancy if pregnancy occurs with IUS in situ, irregular bleeding, and ovarian cysts. Not for emergency/post-coital contraception.International label, same product · MHRA / eMC (Bayer plc)

• CYP3A4 inducers (e.g. phenytoin, carbamazepine, rifampicin, St John's wort)ModerateMay increase levonorgestrel clearance; influence on Mirena contraceptive efficacy not studied but believed not major due to local action.MHRA / eMC (Bayer plc)

• Contraindicated in pregnancy. If pregnancy occurs with Mirena in situ, remove as soon as possible (risk of abortion/preterm labour); exclude ectopic pregnancy. Isolated cases of female foetal masculinisation reported with LNG-IUS in situ.International label, same product · MHRA / eMC (Bayer plc)
• About 0.1% of the levonorgestrel dose transfers in breast milk; unlikely risk to the infant at IUS doses. Progestogen-only methods do not appear to affect milk quantity/quality.International label, same product · MHRA / eMC (Bayer plc)

• Levonorgestrel: Local endometrial suppression, cervical mucus thickening, and ovulation suppression in some women (UK Mirena SmPC).