سعر ميكوسبور 1% محلول 15مل 2022

Mycospor bifonazole 1% topical solution, 15 ml (Hikma Pharma / Bayer Healthcare); imidazole antifungal for fungal skin infections.

• Spontaneous reports (frequency not known): application-site pain and oedema, contact or allergic dermatitis, erythema, pruritus, rash, urticaria, blisters, exfoliation, eczema, dry skin, irritation, maceration and burning; very rarely systemic hypersensitivity. Effects are reversible after stopping.General active-ingredient information · electronic medicines compendium (emc)

• Hypersensitivity to bifonazole or to any excipient; treatment of infants with nappy rash; treatment of nail and scalp infections (UK cream SmPC).General active-ingredient information · electronic medicines compendium (emc)

• Use with caution in patients with a history of hypersensitivity to other imidazole antifungals (e.g. econazole, clotrimazole, miconazole).General active-ingredient information · electronic medicines compendium (emc)

• WarfarinLimited data suggest topical bifonazole may increase the INR in patients on warfarin; monitor appropriately, more closely with occlusion, large surface areas or broken skin.electronic medicines compendium (emc)

• No clinical data in pregnant women; animal reproductive toxicity occurred only at high oral doses and is not expected at the low systemic exposure after topical use. Use in pregnancy only after a doctor has evaluated benefit and fetal risk.General active-ingredient information · electronic medicines compendium (emc)
• Unknown whether bifonazole passes into human milk after topical use (excreted in animal milk after IV dosing); a risk to the infant cannot be excluded, so decide whether to stop breastfeeding or therapy; do not apply to the chest area while breastfeeding.General active-ingredient information · electronic medicines compendium (emc)

• Bifonazole: Imidazole derivative that inhibits ergosterol biosynthesis at two different levels, causing structural and functional impairment of the fungal cytoplasmic membrane (UK SmPC).