سعر نيوتيجازون 25مجم 30 كبسولة 2022

Neotigason 25 mg capsules, pack of 30 (Actavis; Multipharma, Egypt): acitretin oral retinoid for severe psoriasis.

• Treatment of severe psoriasis in adults (prescribe only by those knowledgeable in systemic retinoids).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Many adverse reactions resemble hypervitaminosis A (mucocutaneous, musculoskeletal, hepatic, neuropsychiatric effects); postmarketing reports include myocardial infarction, thromboembolism, stroke, hypersensitivity and myopathy with peripheral neuropathy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregnancy, intention to become pregnant during therapy or within 3 years after stopping, or inability to use reliable contraception.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Severely impaired liver or kidney function; chronic abnormally elevated blood lipids; concomitant methotrexate or tetracyclines; hypersensitivity to acitretin, excipients or other retinoids.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: severe birth defects; females must not drink ethanol during therapy and for 2 months after (ethanol forms etretinate, prolonging teratogenic risk).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hepatotoxicity (including toxic hepatitis), lipid elevations and possible cardiovascular effects, pseudotumor cerebri, and psychiatric events have been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• EthanolConcurrent ethanol leads to formation of etretinate, which has a much longer half-life.DailyMed (U.S. National Library of Medicine)
• MethotrexateCombination contraindicated (increased risk of hepatitis).DailyMed (U.S. National Library of Medicine)
• TetracyclinesCombination contraindicated (both can increase intracranial pressure).DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy: major human fetal abnormalities reported; avoid pregnancy during treatment and for at least 3 years after discontinuation.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Acitretin has been reported in human milk; nursing mothers should not receive acitretin before or during nursing.International label, same formulation · DailyMed (U.S. National Library of Medicine)

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