سعر سورين 25مجم 10 كبسول 2022

Oral acitretin 25 mg capsules (systemic retinoid) marketed in Egypt by International Drug Agency (IDI); pack of 10 capsules.

• Severe psoriasis in adultsPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Many adverse reactions resemble hypervitaminosis A (mucocutaneous, musculoskeletal, hepatic, neuropsychiatric); postmarketing reports include myocardial infarction, thromboembolism, stroke, hypersensitivity, and aggressive feelings/suicidal thoughts.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregnancy, intention to become pregnant during therapy or within 3 years after stopping, or inability to use reliable contraception during and for 3 years after treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Severely impaired liver or kidney function; chronically elevated blood lipids; concomitant methotrexate or tetracyclines; hypersensitivity to acitretin, excipients or other retinoids.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: severe birth defects; female patients of childbearing potential must not ingest ethanol during treatment and for 2 months after stopping (ethanol promotes formation of etretinate).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hepatotoxicity (including toxic hepatitis) has been reported; liver function should be checked.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• EthanolConcurrent ethanol use is associated with formation of etretinate, which has a much longer half-life.DailyMed (U.S. National Library of Medicine)
• MethotrexateCombination contraindicated because of increased risk of hepatitis.DailyMed (U.S. National Library of Medicine)
• TetracyclinesCombination contraindicated: both can increase intracranial pressure.DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy: major human fetal abnormalities reported; pregnancy must be avoided for at least 3 years after discontinuation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Acitretin: Mechanism unknown per US label; acts as a retinoid.