سعر نيكسيبرو 20/1680مجم 7 اكياس 2023

Nexipro 20/1680 mg sachets (Marcyrl/Pharma Right, Egypt): immediate-release omeprazole with sodium bicarbonate powder for oral suspension; 7 sachets.

• Short-term treatment of active duodenal ulcer in adults (most heal within 4 weeks).Population: AdultsDailyMed (NLM)
• Short-term (4-8 weeks) treatment of active benign gastric ulcer in adults.Population: AdultsDailyMed (NLM)
• Treatment of heartburn and other GERD symptoms for up to 4 weeks in adults.Population: AdultsDailyMed (NLM)

• Most common (>=2%): headache, abdominal pain, nausea, diarrhea, vomiting and flatulence.International label, equivalent formulation · DailyMed (NLM)

• Known hypersensitivity to substituted benzimidazoles or any component (anaphylaxis, angioedema, bronchospasm, acute tubulointerstitial nephritis, urticaria); patients receiving rilpivirine-containing products.International label, equivalent formulation · DailyMed (NLM)

• Sodium bicarbonate buffer: each 20 mg or 40 mg oral-suspension packet contains 1,680 mg (20 mEq) sodium bicarbonate, i.e. 460 mg sodium; consider in sodium-restricted diets and avoid in Bartter syndrome, hypokalemia, hypocalcemia and acid-base disorders.International label, equivalent formulation · DailyMed (NLM)
• PPI class warnings: symptomatic response does not exclude gastric malignancy; acute tubulointerstitial nephritis; C. difficile-associated diarrhea; osteoporosis-related fractures with long-term/multiple daily dosing; severe cutaneous adverse reactions; cutaneous/systemic lupus; avoid clopidogrel, St John's wort and rifampin; vitamin B12 deficiency with long-term use; hypomagnesemia; chromogranin A interference.International label, equivalent formulation · DailyMed (NLM)

• ClopidogrelAvoid concomitant use (reduced antiplatelet activity).DailyMed (NLM)
• Rilpivirine-containing productsContraindicated.DailyMed (NLM)

• No adequate and well-controlled studies with the omeprazole/sodium bicarbonate combination in pregnant women; epidemiologic data fail to show increased risk of major malformations with first-trimester omeprazole.International label, equivalent formulation · DailyMed (NLM)
• Both omeprazole and sodium bicarbonate appear to be present in human milk; no clinical data on effects on the breastfed infant or milk production.International label, equivalent formulation · DailyMed (NLM)

• Omeprazole: Suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase (proton pump) at the secretory surface of the parietal cell.
• Sodium bicarbonate: Raises gastric pH and thus protects omeprazole from acid degradation in this immediate-release formulation.