سعر داونوبرازول 40/1680 مجم بودرة معلق فموي 7 أكياس 2024

Downoprazol 40/1680mg pd. for oral susp. 7 sachets — omeprazole 40 mg with sodium bicarbonate 1680 mg (Medizen / Utopia Pharmaceuticals).

• Adults: active duodenal ulcer; active benign gastric ulcer; erosive esophagitis due to acid-mediated GERD; maintenance of healing of EE; (powder) reduction of risk of upper GI bleeding in critically ill (US Zegerid).DailyMed / FDA

• PPI adverse reactions include headache, abdominal pain, nausea, diarrhea, vomiting, flatulence (US Zegerid).International label, same formulation · DailyMed / FDA

• Known hypersensitivity to any component; patients receiving rilpivirine-containing products (US Zegerid).International label, same formulation · DailyMed / FDA

• Symptomatic response does not exclude gastric malignancy; acute TIN; consider sodium load; C. difficile diarrhea; bone fracture with long-term PPI; hypomagnesemia; avoid with clopidogrel; B12 deficiency risk (US Zegerid).International label, same formulation · DailyMed / FDA

• Rilpivirine-containing productsMajorContraindicated — PPIs reduce rilpivirine exposure (US Zegerid).DailyMed / FDA
• ClopidogrelMajorAvoid concomitant use; may reduce antiplatelet effect (US Zegerid).DailyMed / FDA

• Omeprazole: Suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase (proton pump) at the secretory surface of the gastric parietal cell (US Zegerid label).
• Sodium bicarbonate: Raises gastric pH, protecting acid-labile omeprazole from degradation in the stomach so it can be absorbed without an enteric coating (US Zegerid label).