سعر نورميسار 40مجم 30 اقراص 2022

Egyptian olmesartan medoxomil 40 mg film-coated tablets, pack of 30 (Jedco / Four A Pharma).

• Essential hypertension / hypertension in adults (and pediatric ≥6 years per intl labels)Population: Adults; pediatrics per labelMHRA eMC, DailyMed (U.S. NLM)

• Most commonly reported with olmesartan: headache, influenza-like symptoms, dizziness (UK). US: most common adverse reaction in adults was dizziness (3%).International label, same formulation · MHRA eMC, DailyMed (U.S. NLM)

• Hypersensitivity to olmesartan medoxomil or excipients; second and third trimesters of pregnancy; biliary obstruction. Concomitant aliskiren in diabetes or renal impairment (GFR <60) per UK SmPC. US: do not co-administer aliskiren in patients with diabetes.International label, same formulation · MHRA eMC, DailyMed (U.S. NLM)

• Fetal toxicity (discontinue when pregnancy detected). Hypotension in volume/salt-depleted patients. Monitor renal function. Sprue-like enteropathy reported — consider alternative therapy if no other etiology. Hyperkalaemia risk.International label, same formulation · MHRA eMC, DailyMed (U.S. NLM)

• Drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus. When pregnancy is detected, discontinue olmesartan as soon as possible. UK: contraindicated in 2nd/3rd trimester; not recommended in 1st trimester.International label, same formulation · MHRA eMC, DailyMed (U.S. NLM)
• US label: choose to discontinue nursing or the drug. Confirm local advice.International label, same formulation · DailyMed (U.S. NLM)

• Olmesartan medoxomil: Prodrug hydrolysed to olmesartan, which blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II at the AT1 receptor.