سعر لوزابريس 25مجم 7 اقراص 2022

Lozapress 25mg 7 f.c. tab (Egypt; Sigma): film-coated tablets containing losartan potassium 25 mg, an angiotensin II receptor blocker used for hypertension.

• Treatment of hypertension in adults and children 6 years and older, to lower blood pressure and reduce the risk of cardiovascular events, primarily strokes and myocardial infarctions.Population: Adults and children 6 years and olderDailyMed (U.S. National Library of Medicine)
• Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy (evidence suggests this benefit does not apply to Black patients).Population: AdultsDailyMed (U.S. National Library of Medicine)
• Diabetic nephropathy with elevated serum creatinine and proteinuria in type 2 diabetes with a history of hypertension.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypertension trials (>=2% and more than placebo): dizziness, upper respiratory infection, nasal congestion, back pain. Postmarketing: angioedema, hepatitis, thrombocytopenia, hyponatremia, rhabdomyolysis, dysgeusia, erythroderma.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component; coadministration with aliskiren in patients with diabetes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fetal toxicity - discontinue as soon as possible when pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension in volume- or salt-depleted patients (correct before starting); renal function deterioration including acute renal failure in at-risk patients; hyperkalemia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Agents increasing serum potassium (potassium-sparing diuretics, potassium supplements, salt substitutes)May lead to hyperkalemia; monitor potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreases in serum lithium and lithium toxicity reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including selective COX-2 inhibitorsMay deteriorate renal function in elderly, volume-depleted or renally impaired patients and attenuate the antihypertensive effect.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm: drugs acting on the renin-angiotensin system in the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; discontinue as soon as possible when pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether excreted in human milk (significant levels in rat milk); decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Losartan potassium: Losartan and its principal active metabolite selectively block binding of angiotensin II to the AT1 receptor, blocking its vasoconstrictor and aldosterone-secreting effects.