سعر نورميكس 200مجم 12 قرص 2026

Rifaximin 200 mg film-coated tablets, pack of 12 (Alfasigma; distributed in Egypt by United Company for Trading & Distribution); poorly absorbed rifamycin antibiotic for travelers' diarrhoea.

• Treatment of travelers' diarrhoea caused by noninvasive strains of Escherichia coli in adults and children 12 years and older.Population: Adults and children >=12 yearsDailyMed (U.S. National Library of Medicine)

• Travelers' diarrhoea trials: headache was the most common adverse reaction (>=2%).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to rifaximin, any rifamycin antimicrobial agent or any component (reactions have included exfoliative dermatitis, angioneurotic oedema and anaphylaxis).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Not effective in diarrhoea complicated by fever and/or blood in the stool or caused by pathogens other than E. coli; discontinue if symptoms worsen or persist beyond 24-48 hours.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea may occur; evaluate if diarrhoea occurs or worsens during or after therapy.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Use with caution in severe (Child-Pugh C) hepatic impairment and with P-glycoprotein inhibitors such as ciclosporin.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• P-glycoprotein inhibitors (e.g. ciclosporin)Caution when rifaximin is used together with a P-glycoprotein inhibitor (systemic exposure may increase).DailyMed (U.S. National Library of Medicine)

• No available human pregnancy data; rifaximin was teratogenic in rats and rabbits (ocular, oral/maxillofacial, cardiac and lumbar spine malformations). Advise pregnant women of the potential risk to a fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Rifaximin: Binds bacterial DNA-dependent RNA polymerase beta-subunit, inhibiting transcription and bacterial protein synthesis; minimal systemic absorption after oral dosing.