سعر فاتروكسيم 200مجم 10 اقراص 2024

Rifaximin 200 mg oral film-coated tablets (ATM / EGPI), pack of 10.

• Treatment of travelers' diarrhea caused by noninvasive strains of Escherichia coli in adults and children 12 years and older (not for diarrhea with fever or blood in the stool, or due to other pathogens).DailyMed (U.S. NLM)

• Travelers' diarrhea trials: headache was the adverse reaction occurring at 2% or more and above placebo (10% vs 9%). Post-marketing: hypersensitivity (exfoliative dermatitis, rash, angioedema, urticaria, flushing, pruritus, anaphylaxis), C. difficile colitis, SJS/TEN, rhabdomyolysis in patients with cirrhosis.International label, same formulation · DailyMed (U.S. NLM)

• Hypersensitivity to rifaximin, any rifamycin antimicrobial agent or any component (reactions have included exfoliative dermatitis, angioneurotic oedema and anaphylaxis).International label, same formulation · DailyMed (U.S. NLM)

• Not effective in diarrhea complicated by fever and/or blood in the stool or due to pathogens other than E. coli (e.g. Campylobacter jejuni; Shigella and Salmonella not proven); discontinue if symptoms worsen or persist beyond 24-48 hours.International label, same formulation · DailyMed (U.S. NLM)
• Clostridioides difficile-associated diarrhoea has been reported and may range from mild diarrhoea to fatal colitis; consider CDAD in any patient with diarrhoea after antibiotic use.International label, same formulation · DailyMed (U.S. NLM)
• Use only for proven or strongly suspected bacterial infection to reduce development of drug-resistant bacteria.International label, same formulation · DailyMed (U.S. NLM)

• P-glycoprotein inhibitors (cyclosporine)Cyclosporine significantly increased systemic rifaximin exposure; caution, especially with hepatic impairment.DailyMed (U.S. NLM)
• WarfarinChanges in INR reported post-marketing; monitor INR and prothrombin time and adjust warfarin if needed.DailyMed (U.S. NLM)

• No human data to inform drug-associated risk; teratogenic effects (ocular, oral/maxillofacial, cardiac and lumbar spine malformations) were seen in rats and rabbits. Advise pregnant women of the potential risk to a fetus.International label, same formulation · DailyMed (U.S. NLM)
• No information on presence in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against the mother's need and potential infant effects.International label, same formulation · DailyMed (U.S. NLM)

• Rifaximin: Binds the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis; minimal systemic absorption after oral dosing.