سعر اومنيك اوكاس 0.4 مجم 2024

Tamsulosin 0.4 mg film-coated prolonged-release tablets (OCAS), alpha-1 blocker for symptoms of benign prostatic hyperplasia, box of 30 tablets (3 strips), Astellas, imported product.

• Treatment of functional symptoms of benign prostatic hyperplasia (BPH)Population: Adult menelectronic medicines compendium (emc)

• Common: dizziness (1.3%) and ejaculation disorders (retrograde ejaculation, ejaculation failure). Uncommon: headache, palpitations, orthostatic hypotension, rhinitis, constipation, diarrhoea, nausea, vomiting, rash, pruritus, urticaria, asthenia. Rare: syncope, angioedema. Very rare: priapism, Stevens-Johnson syndrome.International label, same formulation · electronic medicines compendium (emc)

• History of orthostatic hypotension; severe hepatic insufficiency; hypersensitivity to tamsulosin or any excipient.International label, same formulation · electronic medicines compendium (emc)

• Blood pressure reduction and, rarely, syncope may occur; exclude other causes of BPH-like symptoms (digital rectal examination and PSA as needed); caution in severe renal impairment (CrCl <10 ml/min); intraoperative floppy iris syndrome during cataract or glaucoma surgery.International label, same formulation · electronic medicines compendium (emc)

• Strong CYP3A4 inhibitors (e.g. ketoconazole)Increase tamsulosin exposure (ketoconazole raised AUC 2.8-fold); do not combine with strong CYP3A4 inhibitors in CYP2D6 poor metabolisers and use with caution otherwise.electronic medicines compendium (emc)
• Other alpha-1 adrenoceptor antagonistsConcomitant use could lead to hypotensive effects (SmPC section 4.5).electronic medicines compendium (emc)

• Not indicated for use in women.International label, same formulation · electronic medicines compendium (emc)

• Tamsulosin: Binds selectively and competitively to postsynaptic alpha-1 receptors, in particular alpha-1A, relaxing prostatic and urethral smooth muscle (UK SmPC 5.1).