سعر اوريجين-ك1 10مجم 30 اقراص 2022

Phytomenadione (vitamin K1) 10 mg film-coated chewable tablets, pack of 30.

• Coagulation disorders due to vitamin K deficiency or interference with vitamin K activity (e.g. anticoagulant-induced hypoprothrombinaemia)Population: AdultsDailyMed (US National Library of Medicine)

• Contraindicated in patients with a history of hypersensitivity to phytonadione or any inactive ingredient.General active-ingredient information · DailyMed (US National Library of Medicine)

• Oral phytonadione does not counteract heparin; the effect on INR is not immediate (1-8 hours). Over-correction of anticoagulant-induced hypoprothrombinaemia may restore pre-existing thrombotic risk; keep doses as low as possible and check prothrombin time regularly.General active-ingredient information · DailyMed (US National Library of Medicine)
• Avoid the oral route when absorption is impaired; bile salts must be given with oral tablets when endogenous bile supply is deficient.General active-ingredient information · DailyMed (US National Library of Medicine)

• Coumarin/indanedione anticoagulants (e.g. warfarin)Phytonadione may induce temporary resistance to prothrombin-depressing anticoagulants, especially at larger doses; higher anticoagulant doses or a different anticoagulant class may be needed.DailyMed (US National Library of Medicine)

• Vitamin K1 (phytomenadione): Cofactor for hepatic gamma-carboxylation of clotting factors II, VII, IX and X.